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Andarine S4 is mostly used in laboratory research and has a high binding affinity for androgen receptors in skeletal muscle and bone tissues. Research indicates that strategically stimulating these receptors may promote lean muscle growth, increase bone density, and improve overall physical performance.

Size: 1g | 3g

437 in stock

First time customer gets 15% discount code = 1storder

S-4 Andarine Sarms Powder

S-4 Andarine Powder is a Selective Androgen Receptor Modulator that has gained popularity for its ability to boost skeletal muscle size and performance. S-4, a SARM, is renowned for its selective binding to androgen receptors in muscle and bone tissues. This specific binding mechanism is anticipated to result in increased muscle size and strength, as well as improved sports performance, while avoiding the detrimental side effects associated with traditional anabolic steroids.

One of S-4’s main advantages is its ability to stimulate muscle growth due to its high androgen binding affinity, which results in bigger muscular tissue size. Furthermore, S-4 has been related to enhanced endurance and stamina, allowing people to do difficult activities with greater energy and resilience.

S-4 Andarine Powder is also known as Acetamidoxolutamide, Androxolutamide, GTx-007, and S-4. It was developed by GTx Inc .

Benefits of  S-4 Andarine SARMS Powder

Muscle Wasting

S-4, exhibits potential in preventing muscle wasting due to its selective androgen receptor modulation properties. By targeting specific androgen receptors in muscle tissues, S-4 stimulates protein synthesis, which plays a crucial role in muscle growth and maintenance. This mechanism enables S-4 Andarine Powder to potentially counteract muscle wasting conditions by promoting muscle preservation and growth even under catabolic states, such as during intense physical activity or certain medical conditions. Research suggests that S-4’s ability to bind selectively to androgen receptors in muscle tissue can help combat muscle loss, making it a promising candidate for individuals looking to preserve lean muscle mass and prevent muscle wasting, particularly in scenarios where muscle breakdown is a concern.

Bone Density

Studies highlighted that S-4’s ability to target specific androgen receptors linked to bone density regulation may lead to an increase in total body bone mineral density. By stimulating these receptors, S-4 potentially promotes bone strength and density, offering benefits in combating conditions like osteoporosis and improving overall bone health. The anabolic effects of S-4 Andarine Powder on bones, demonstrate its potential to prevent bone loss and contribute to the maintenance and enhancement of bone mineral density, making it a promising candidate for individuals seeking to improve bone health and reduce the risk of bone-related issues.

Increased Muscle Mass

Studies show that S-4 can effectively contribute to increased muscle growth. By selectively binding to androgen receptors in muscle tissues, S-4 stimulates protein synthesis, a crucial process for muscle development and repair. This targeted mechanism allows S-4 to promote lean muscle mass gains, aiding users in achieving their fitness goals. Additionally, the anabolic properties indicate its potential to support muscle growth even during caloric deficits, making it a valuable supplement for individuals looking to enhance muscle size and strength. The ability of S-4 Andarine Powder to stimulate muscle growth while potentially avoiding detrimental side effects commonly associated with traditional steroids underscores its appeal among athletes and fitness enthusiasts seeking safe and effective ways to increase muscle mass.

Cut & Bulk

Known for its high oral bioavailability, S-4 Andarine Powder is highly flexible and can be used to cut, recompose or bulk.

Weight Loss

S-4,  has been recognized for its potential role in aiding weight loss by targeting specific androgen receptors. By selectively binding to these receptors, S-4 may promote fat breakdown and enhance fat oxidation, potentially contributing to a reduction in body fat, particularly in stubborn areas like the abdomen. The ability of S-4 to support fat loss, coupled with its reported benefits in strength enhancement and muscle preservation, positions it as a promising supplement for those seeking effective weight management solutions.

Like our S-4 Andarine Powder? Shop more Andarine S-4 Liquid products here from Direct SARMS


[1] Selective androgen receptor modulator treatment improves muscle strength and body composition and prevents bone loss in orchidectomized rats. Endocrinology. 2005 Nov;146(11):4887-97 by Gao W, Reiser PJ, Coss CC, Phelps MA, Kearbey JD, Miller DD, Dalton JT.

[2]  Therapies for musculoskeletal disease: can we treat two birds with one stone? Curr Osteoporos Rep. 2014 Jun;12(2):142-53. by Girgis CM, Mokbel N, Digirolamo DJ.

Formula: C19H18F3N3O6

Molar mass: 441.357 g/mol

Do I need PCT & other supplements?

Post-cycle therapy (PCT) is deemed necessary when taking S-4 Andarine, according to scientific research. The administration of PCT alongside S-4 Andarine Powder has been shown to aid in the preservation of muscular mass, fat burning, and an elevation in mood and energy levels.

The use of certain selective androgen receptors (SARMS) may lead to temporary suppression of natural testosterone levels. Therefore, it is imperative to restore testosterone levels to their baseline after completing a SARMS cycle in order to maintain the achieved results. The duration of the PCT should correspond to the duration of the SARMS cycle length.

While a Post Cycle Therapy is not a compulsory requirement during SARMS usage, it is prudent for science researchers to opt for PCT for a duration of at least four weeks, as a precautionary measure. Accordingly, some bodybuilders advocate for the incorporation of a test booster as part of their regimen.

Interested in Sarms Supplements? Check out post cycle therapy, cycle support & test base here.


DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Direct Sarms website is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.



S4 Andarine HPLC Certificate