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CARDARINE GW501516 Capsules


GW501516, also known as Cardarine, is a synthetic compound has demonstrated potential benefits in fat metabolism and fat burning in muscle cells during clinical studies.

– 60 CAPSULES per Bottle | 10mg Per Capsule –

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2 x GW-501516 60 Capsules = $113.22 | Now = $101.90

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GW-501516 Cardarine Capsules

GW-501516, also known as Cardarine, is frequently misidentified as a selective androgen receptor modulator (sarm), but it is actually a peroxisome proliferator-activated receptor (PPAR) agonist. GW-501516 and SARMs share some important characteristics, but there are significant differences. For instance, GW-501516 has a negligible effect on testosterone levels and androgen receptors. GW-501516 Cardarine Capsules have acquired popularity due to their ability to increase the body’s fatty acid metabolism.

In this manner, GW-501516 Cardarine capsules increases gene expression and allows the body to discharge energy even when at rest. As a result, athletes and bodybuilders receive energy boosts for intense exercises that they would not otherwise obtain through regular activity.

In 1992, Cardarine was developed as a potential therapeutic approach for addressing a range of metabolic diseases and cardiovascular ailments as it helps to decrease poor cholesterol levels and higher levels of good cholesterol. According to studies, it may also inhibit the development of prostate, colon, and breast cancers.

Benefits of GW-501516 Cardarine Capsules SARMs

Metabolic Disorders

A recent study examined the impact of Cardarine administration on metabolic disorders in males. The findings indicated that a two-week GW501516 treatment improved various metabolic abnormalities such as obesity, insulin resistance, and oxidative stress.

Further randomized trials and research are warranted to evaluate the potential efficacy of this compound in enhancing physical function and health outcomes in specific populations.

Burns Fat

The primary advantage of PPAR agonists such as GW501516, is its fat burning capacity to eliminate unhealthy fat. This is accomplished by inhibiting the formation of fatty acid chains and fat storage in the body. Research chemicals Cardarine stimulates AMP-activated protein kinase in skeletal muscle tissue and stimulates glucose uptake, reprogramming the body’s metabolism to burn body fat for energy instead of muscle protein or carbohydrates.

GW-501516 Cardarine Capsules can enhance lipolysis and improve insulin sensitivity, lipid homeostasis, and glucose tolerance. It may one day be used to treat type II diabetes based on its beneficial effects on insulin and blood glucose levels.

According to a study on rhesus monkeys, it could be used as a source of energy to compensate for the decreased food intake. Cardarine has been shown to possess cardioprotective properties by substantially elevating hdl cholesterol (the type you want to be elevated).

Enhances Muscular Hypertrophy

According to research, GW-501516 Cardarine capsules increased oxygen consumption in the muscle’s titch fibres, which improved endurance. Research shows it is possible to train at a low intensity for protracted periods with brief rest periods. Additionally, cardarine increases glycogen storage within muscle tissue, resulting in fuller muscles throughout the cycle.

GW-501516 Cardarine capsules may be beneficial for individuals who desire toned, defined muscles and are susceptible to glycogen depletion due to calorie restriction.

Enhanced Tissue Regeneration

Laboratory research suggests that GW-501516 Cardarine Capsules improves the recuperation time of muscles and the health of the liver. As a result, athletes and bodybuilders benefit from a rapid recovery period following workouts, which also shortens the periods between training sessions.

The overstimulation of the androgen receptor by anabolic steroids and selective androgen receptor modulators (SARMs) suppresses endogenous testosterone levels. Due to the fact that PPARd agonists have no effect on the HPT (hypothalamic-pituitary-testicular) axis, testosterone levels will remain stable while taking cardarine.

Increase Endurance

Animal studies have shown that Cardarine can have positive effects on enhancing running endurance. GW-501516 Cardarine capsules is a peroxisome proliferator-activated receptor delta (PPARδ) agonist that directly stimulates glucose transport and enhances oxidative capacity in skeletal muscle. This mechanism of action leads to improved fatty acid oxidation and increased oxidative capacity, ultimately enhancing endurance performance.

The activation of PPARδ by GW-501516 has been shown to enhance endurance in rodent models by increasing metabolic gene expression and promoting the formation of oxidative myofibers. In fact, a study on adult Kunming mice demonstrated that GW-501516 treatment resulted in a 44% increase in running endurance and muscular endurance.


A groundbreaking study in 2023 revealed that GW-501516 Cardarine Capsules, a PPARδ agonist, exhibits remarkable antifibrotic effects in an in vitro model of bronchial subepithelial fibrosis. These findings indicate the immense potential of GW-501516 in revolutionizing the treatment of subepithelial fibrosis associated with asthma. Such promising results pave the way for a novel and effective therapeutic approach for this condition.

Please note that GW-501516 is currently restricted to research purposes and has not been granted FDA approval for human consumption. Clinical trials are required to thoroughly evaluate its prolonged safety and potential side effects.

Like our GW-501536 Cardarine Capsules? Shop more GW-501516 products here from Direct SARMS


[1] A metabolomic study of the PPARδ agonist GW501516 for enhancing running endurance in Kunming mice, Sci Rep. 2015; 5: 9884. by Wei Chen,  Rong Gao et al.

[2] Molecular and Cellular Regulation of Adaptation to Exercise, Progress in Molecular Biology and Translational Science, 2015 by Robert C. Noland

[3] PPARδ agonists have opposing effects on insulin resistance in high fat-fed rats and mice due to different metabolic responses in muscle, Br J Pharmacol. 2011 Jun; 163(3): 556–566. by Ji-Ming Ye,  Jennifer Tid-Ang, et al.

[4] PPARδ Agonist GW501516 Suppresses the TGF-β-Induced Profibrotic Response of Human Bronchial Fibroblasts from Asthmatic Patients, Int J Mol Sci
. 2023 Apr 23;24(9):7721. by Milena Paw, Dawid Wnuk, Zbigniew Madeja, Marta Michalik

Molecular Formula: 
Molecular Weight: 453.498 g/mol

60 CAPSULES per Bottle | 10mg Per Capsule

Do I need PCT & other Supplements?

Post-cycle therapy (PCT) is deemed necessary when taking GW-510516 Cardarine capsules, according to scientific research. The administration of PCT alongside Cardarine has been shown to aid in the preservation of muscular mass, fat burning, and an elevation in mood and energy levels.

The use of certain Selective Androgen Receptor Modulators (SARMS) may lead to temporary suppression of natural testosterone levels. Therefore, it is imperative to restore testosterone levels to their baseline after completing a SARMS cycle in order to maintain the achieved results. The duration of the PCT should correspond to the duration of the SARMS cycle.

While a Post Cycle Therapy is not a compulsory requirement during SARMS usage, it is prudent for science researchers to opt for PCT for a duration of at least four weeks, as a precautionary measure. Accordingly, some bodybuilders advocate for the incorporation of a test booster as part of their regimen.

Interested in Sarms Supplements? Check out post cycle therapy, cycle support & test base here.


DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Direct Sarms website is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.

All images are for display purposes only. The products you receive may differ slightly from the images. But the quality always remands as a premium product.


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