B7-33 Peptide Vial
B7-33 peptide is a formed as a single-chain peptide synthesised from H2-relaxin (human relaxin 2), a naturally occurring essential water-soluble protein known for its anti-fibrotic effects. B7-33 retains its sedative properties despite having no effect on cAMP synthesis. However, the stimulation of ERK1/2 phosphorylation by this peptide increases MMP2 synthesis and collagen degradation.
Asides from H2-relaxin included in the relaxin protein family are relaxin, insulin-like peptide 3, H3-relaxin, and insulin-like peptide 5.
There have been documented musculoskeletal, cardiovascular, and reproductive effects of insulin-related proteins in animal studies.
According to research and investigation, B7-33 peptide has many benefits, including a reduction in fibrinolysis in acute and chronic diseases including lung inflammation. It has also shown promise as a treatment for vascular diseases, including the prevention of cardiac injury-related scarring in animal models.
B7-33 Peptide Vial Benefits
Anti-inflammatory and wound healing qualities.
Relaxin receptors have multiple additional activities. In addition to cAMP, corticotropin-releasing factor (CRF), insulin-like peptides can also activate these receptors.
It has been demonstrated that activators possess anti-inflammatory, antioxidative, and wound-healing effects. Following these discoveries, Relaxin became the primary ligand for these receptors. In addition, these substances have anti-fibrotic effects.
According to research, Relaxin is a vasodilator, a stimulant of blood vessel development, and an antihypertensive. Due to these roles, Relaxin possesses potent anti-fibrotic capabilities and is being studied as a potential treatment for acute heart failure and other fibrotic illnesses.
Reduction of Scar Tissue
After cardiac damage, in clinical trials using mouse models, B7-33 Peptide has been demonstrated to minimise excessive scar tissue production. It has also shown promise in improving cardiac function and treating vascular diseases and preeclampsia in pregnancy.
Decreased fibrosis
B7-33 possesses strong anti-fibrotic effects. Therefore, active research is being conducted into fibrosis reduction for acute and chronic disorders such as heart failure, lung inflammation, and renal disease.
For the first time, B7-33 peptide can be used to treat heart failure in animals, resulting in a longer survival after injury and improved quality of life.
There is also the option to buy B7-33 Nasal Spray and B7-33 Pre Mixed Pen for research purposes.
References:
[1] https://pubmed.ncbi.nlm.nih.gov/ 32295457/
[2] https://pubmed.ncbi.nlm.nih.gov/ 28478069/
Sequence: VIKLSGRELVRAQIAISGMSTWSKRSL
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