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Aicar Nasal Spray


AICAR peptide nasal spray presents potential benefits in enhancing endurance, promoting fat oxidation, and potentially improving metabolic functions.


15ml Nasal Spray contains 50mg AICAR

30ml Nasal Spray contains 100mg AICAR

Out of stock

First time customer gets 15% discount code = 1storder

Aicar Nasal Spray

AICAR Nasal Spray peptide, also referred to as 5-Aminoimidazole-4-carboxamide ribonucleotide, acts as a powerful activator of AMP-activated protein kinase (AMPK). By penetrating cells and stimulating AMPK, this peptide plays a crucial role in regulating metabolism. AMPK is typically activated during periods of low energy and functions to inhibit anabolic metabolism. AICAR effectively activates AMPK, replicating the effects of exercise in the body. This leads to muscle cells independently absorbing glucose without the need for insulin.

AICAR, also known as AICA ribonucleotide, is instrumental in enhancing endurance and reducing stored fat. Research indicates that AICAR facilitates the breakdown of fat by mobilizing it into mitochondria, resulting in the release of stored energy. Animal studies have demonstrated the ability of AICAR to activate metabolic genes, thereby enhancing exercise endurance. It is worth noting that even inactive animals experienced increased endurance when exposed to this compound.

Scientific research consistently proves that our compound has the ability to reduce cell swelling and promote the healing of damaged cells. Clinical trials involving AICAR have also shown its potential to regulate blood sugar in individuals with diabetes, making it effective in preventing and treating type II diabetes. These results indicate the significant role of our peptide in managing blood sugar levels and thus insulin resistance.

Furthermore, extensive scientific research has demonstrated that AICAR is highly effective in protecting the heart from ischemic injury and improving heart safety during coronary bypass surgery. Studies have also found that AICAR can mimic the metabolic changes seen in exercising muscles, even without prior physical activity. Additionally, AICAR has anti-inflammatory properties, reducing inflammation by blocking the molecules responsible for triggering an immune response. In conclusion, the use of AICAR nasal spray offers multiple benefits, including tissue healing, fat burning, muscle stimulation, and inflammation reduction.

Aicar Nasal Spray Benefits

Increasing Muscle Mass:

Research has shown that AICAR research peptides play a vital role in enhancing muscle mass and are essential for both muscle growth and maintaining muscle mass. In addition, AICAR has the potential to prevent muscle loss that commonly occurs with aging.

In addition, research has highlighted the significant role of AMPK in slowing down muscle wasting. Mice lacking this protein experienced more muscle weakness than anticipated.

These findings suggest that AICAR could potentially be used as a treatment for muscle wasting diseases in the future. Moreover, when combined with intense exercise, AICAR’s muscle growth effects are significantly amplified.

Anti-Inflammatory Benefits:

Clinical research has provided evidence to support the vital role of AICAR in addressing cellular inflammation. AICAR, which shares similarities to the widely-used diabetes medication metformin, offers its efficacy through its anti-inflammatory properties.

Importantly, AICAR has been proven to offer protection against inflammatory diseases such as asthma, colitis, hepatitis, and atherosclerosis. Studies involving animals have even shown that AICAR can reduce inflammation in colitis.

Furthermore, recent scientific research conducted suggests that AICAR nasal spray holds potential as a mediator in addressing autoimmune diseases and various other inflammatory conditions.


The efficacy of AICAR, an AMPK activator, in enhancing sperm motility, metabolism, and fertilizing ability has been observed in cats, chickens, and goats. When administered orally, AICAR exhibits minimal adverse effects and exhibits a high level of bioavailability in mice.

Improvement of Insulin Sensitivity:

Through scientific research, the efficacy of AICAR nasal spray in reducing inflammation in fat tissue, which is linked to insulin resistance, has been established. This anti-inflammatory effect is mediated via distinct pathways involving SIRT1 and adipose tissue macrophages.

Additional research on obese primates has provided evidence of the beneficial effects of AICAR, including weight loss and improved insulin sensitivity.

Multiple studies by reputable institutions have shown that AICAR not only decreases inflammation in metabolic disorders, but also enhances insulin sensitivity, lipid metabolism, energy balance, and inflammatory symptoms in both healthy and diabetic mice.

Cardiovascular Disease Prevention:

Inflammation is a frequent contributor to heart disease. The substance AICAR, which is renowned for its potent anti-inflammatory properties, has the potential to halt the progression of vascular diseases.

To investigate this further, researchers utilized rodent models of atherosclerosis in a study. The results demonstrated that administration of AICAR effectively inhibited the proliferation of vascular smooth muscle, resulting in a reduction of short- and long-term stent-related complications.

In addition, the study revealed that activating AICAR suppresses immune responses associated with atherosclerosis. AICAR may prevent heart attacks by reducing the proliferation of macrophages caused by the accumulation of LDL cholesterol.

These results indicate that AICAR nasal spray peptide could be a potential treatment for delaying the progression of heart disease and lowering the risk of heart attacks.

Cancer Cells Reduction:

The multi-faceted role of the AICAR hormone peptide in cancer growth is the focus of recent research. This peptide has been found to have the ability to either slow down or speed up tumor growth, depending on specific circumstances.

When the AMPK enzyme is activated for a prolonged period, it can effectively inhibit the metabolism of cancer cells, leading to their death.

Moreover, researchers at are currently investigating the potential of combining AICAR with other chemotherapy drugs to enhance their effectiveness. They believe that using an AICAR nasal spray peptide has the potential to:

  • Minimize negative side effects
  • Improve the prognosis of patients with tumors that are resistant to chemotherapy
  • Allow for lower doses of these compounds to be used.

Recent studies have shown that AICAR has the potential to induce programmed cell death specifically in thyroid cancer cells. This occurs through the accumulation of p21. Promisingly, experts believe that utilizing an AICAR nasal spray could effectively hinder the growth and survival of cancer cells overall.

There is also the option to buy Aicar Peptide Vial or buy Aicar Pre Mixed Peptide Pen.

Sequence: 5-Aminoimidazole-4-carboxamide ribonucleotide

Molecular Formula: C9H15N4O8P

Molecular Weight: 338.21 g/mol

Storage: Lyophilized peptides to be stored below -18°C


[1] https://www.ncbi.nlm.nih.gov/ pubmed/19853624

[2] https://pubmed.ncbi.nlm.nih.gov/ 20844264/

[3] https://pubmed.ncbi.nlm.nih.gov/ 22324445/


DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Direct Sarms website is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.

All images are for display purposes only. The products you receive may differ slightly from the images. But the quality always remands as a premium product.